2024 Qsymia long term side effects

Indeed, in the wake of the fen-phen problems, the FDA rejected all drug company efforts to win approval for new weight-loss drugs between 1999 and 2012. Since then, it has approved four drugs for .... Still

Oct 27, 2021 · Introduction. The worldwide prevalence of overweight and obesity, defined as having a body mass index (BMI) between 25.0–29.9 kg/m 2 and ≥30.0 kg/m 2, 1 has almost tripled since the 1970s, with nearly 40% of adults being overweight and 13% obese, and these numbers have been steadily increasing. 2 Patients with obesity are at an increased risk of developing comorbidities such as ... In clinical studies, phentermine-topiramate reduced body weight by 8.6% to 9.4% more than placebo using a conservative ITT analysis.108. Phentermine-topiramate carries risks of several serious side effects. Notably, topiramate is a recognized teratogen, at least at the higher doses used for the treatment of epilepsy.Jun 28, 2023 · Extreme happiness or sadness. Symptoms of dangerously high blood pressure, such as severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, or seizures. These symptoms can indicate a serious phentermine side effect. Qsymia side effects can include trouble sleeping if taken in the evening and potential seizures if you stop the medication abruptly. Other side effects can include dizziness, drowsiness, dry mouth, tiredness, tingling of the hands/feet, constipation, and metallic tastes. Some of the more serious side effects can include temporary difficulty ...Jan 16, 2023 · Qsymia is significantly more expensive than phentermine-only pills, costing about $200 per month without insurance. The combined pill has a long list of potential side effects, including severe birth defects if taken while pregnant. This is a newer medication (FDA approval in 2012), so long-term side effects remain relatively unknown. Feb 14, 2023 · Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ... Jun 4, 2020 · This combination consists of fixed lower doses of phentermine and topiramate (3.75/23, 7/46, 11.25/69 and 15/92 mg) and is available in capsules under the brand name Qsymia. Common side effects of phentermine include nervousness, excitability, insomnia, headache, dry mouth, sweating, tachycardia, palpitations, nausea, constipation, and thirst. From research studies, an outline of the common and rare side effects associated with Qsymia is as follows: Common side effects (reported in more than 1% of patients): Paresthesia (tingling, numbness) of the extremities (15-38%) Dizziness (11-28%) Dysgeusia (abnormal taste sensation) (6-19%) Insomnia (7-17%) Constipation (6-16%)Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances.It does not making you lose than reaching the idea, it is a compound that can be able to lose weight. It also leads to by increasing their absorption of physical activity and improvement Qsymia Long Term Side EffectsThe SELECT trial is the long-term cardiovascular outcomes trial for Wegovy that aims to assess its effects on heart disease and stroke in patients with overweight and obesity; it is currently ongoing and expected to be completed in September 2023. Anti-obesity medication management: An evolving landscapePhentermine is an effective weight loss pill, but due to stimulating effects, it may induce withdrawal symptoms in some people. Withdrawal symptoms occur when the brain is trying to adjust to the new situation. Persons experience symptoms such as fatigue, irritability, bad mood, among others.4. Avoid alcohol. Avoid drinking alcohol while taking Qsymia as it can increase your risk of serious side effects, such as central nervous system depression, and an increase in your risk of falls. 5. Don’t skip meals. Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia). 6. It is also commonly prescribed to prevent migraines. Mild topiramate side effects include a “pins and needles” feeling, weight loss, and dizziness. Trouble focusing or thinking are also possible, especially when taking higher doses. High body temperature, suicidal thoughts, and eye problems are rare topiramate side effects.The options have short-term side effects and long-term risks. However, when other weight loss medications and diets have not produced adequate results, doctors may consider surgery.Qsymia works by reducing your appetite. In initial studies, Qsymia helped about 70% of adults lose at least 5% of their body weight after 1 year. Close to 50% of participants lost at least 10% of their body weight. When compared to Contrave, researchers found that Qsymia is usually the more effective option. 3.During the last few decades, some anti-obesity drugs were used to treat morbid obesity; however, many of them were removed from the market owing to long-term side effects, particularly cardiovascular issues . Since then, anti-obesity drug development process focusses on both weight loss efficacy and cardiovascular safety.Aug 3, 2023 · What Is Wegovy? Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e ... Oct 27, 2021 · Introduction. The worldwide prevalence of overweight and obesity, defined as having a body mass index (BMI) between 25.0–29.9 kg/m 2 and ≥30.0 kg/m 2, 1 has almost tripled since the 1970s, with nearly 40% of adults being overweight and 13% obese, and these numbers have been steadily increasing. 2 Patients with obesity are at an increased risk of developing comorbidities such as ... Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ... Approved for long-term use? Yes. Qsymia has much lower amounts of phentermine and topiramate than when these drugs are given alone. Side effects: The most common side effects are tingling hands ... Common Side Effects of Weight Loss Drugs. Increased blood pressure and heart rate, insomnia, nervousness, restlessness, dependence, abuse or withdrawal may occur with long-term use. When given as a single agent, phentermine is not implicated in valvular heart disease; avoid use at bedtime. Aug 4, 2022 · Other side effects. Some side effects of phentermine / topiramate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use.Side effects Interactions FAQ What is Qsymia? Qsymia contains a combination of phentermine and topiramate in an extended-release capsule. Phentermine is an appetite suppressant similar to an amphetamine. Topiramate is typically used as a seizure medication, also called an anticonvulsant.As long as you are not taking the medication continuously with no breaks, and will stop the medication eventually, I believe that this is a safe treatment for you. That being said, you mentioned 5 years in the beginning of the question. If you have been taking the medication 3 months on, 1 month off for 5 years, I would consider that long term ...Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ...Qsymia's results have been clinically tested in two long-term studies with ... QSYMIA CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING: Birth defects (cleft lip/cleft palate). If you take Qsymia during ...Apr 8, 2013 · PHEN is a noradrenergic drug, which is theorized to affect food intake primarily via the enhancement of norepinephrine release and possibly via the blockade of norepinephrine reuptake as well. It has been available in the US since 1959 for short-term (generally regarded as 12 weeks) treatment of obesity in dose range of 15 mg/day to 37.5 mg/day. How Long Will Phentermine Last. This drug’s side effects are mild, including fatigue, dizziness, headache, restlessness, nervousness, impotence, sleepiness, and nausea. Phentermine is generally prescribed by doctors and used for depression that is not responding to other treatments. The drug is also used as a weight-loss aid.Feb 14, 2023 · Summary. Commonly reported side effects of orlistat include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Feb 28, 2023 · The Saxenda Savings Card allows you to pay as little as a $25 copay or save up to $200 per Saxenda prescription. The Savings Card program allows for up to 12 benefits annually. There are eligibility requirements, and other restrictions apply. According to GoodRX, out-of-pocket prices range from $1332.59 to $1432.91. Mar 29, 2022 · Tardive dyskinesia is a movement disorder that is a side effect of medications, especially first-generation antipsychotics. Less common causes are second-generation antipsychotics, antidepressants, mood stabilizers, antiepileptic drugs, movement disorder medications, antiemetics, and decongestants. Two medications have been approved to treat ... Adults Adverse reactions occurring at greater than or equal to 5% and at least 1.5 times placebo in adults include paraesthesia, dizziness, dysgeusia, insomnia, constipation, and dry mouth. Adverse reactions reported in greater than or equal to 2% of QSYMIA-treated adults and more frequently than in the placebo group are shown in Table 3. Table 3.Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ... Common Side Effects of Weight Loss Drugs. Increased blood pressure and heart rate, insomnia, nervousness, restlessness, dependence, abuse or withdrawal may occur with long-term use. When given as a single agent, phentermine is not implicated in valvular heart disease; avoid use at bedtime. Mar 9, 2020 · However, the EMA has not approved this medication due to its abuse potential, the lack of long-term data on the cardiovascular effects of phentermine, and the cognitive side effects of topiramate—attention, language, and memory impairment . As this drug combination contains phentermine, it is a controlled DEA schedule IV substance. Side effects Interactions FAQ What is Qsymia? Qsymia contains a combination of phentermine and topiramate in an extended-release capsule. Phentermine is an appetite suppressant similar to an amphetamine. Topiramate is typically used as a seizure medication, also called an anticonvulsant.Feb 14, 2023 · Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ... tiredness and weakness. trouble thinking, speaking, or walking. upper right abdominal or stomach pain. weak or feeble pulse. weight gain. yellow eyes or skin. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.As long as you are not taking the medication continuously with no breaks, and will stop the medication eventually, I believe that this is a safe treatment for you. That being said, you mentioned 5 years in the beginning of the question. If you have been taking the medication 3 months on, 1 month off for 5 years, I would consider that long term ...It is used by certain overweight people, such as those who are obese or have weight -related medical problems. Losing weight and keeping it off can lessen the many health risks that come with ...1. In 2012, a new medication called Qsymia (with both Adipex and Topamax components) became available for weight loss. It was the first FDA approved weight loss drug in its class. The weight loss pill is a combination of 2 existing drugs: phentermine and topiramate. This combination has been shown to be a good tool for weight loss in addition ...Feb 14, 2023 · Summary. Commonly reported side effects of orlistat include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Uses. This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who ...Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ... May 4, 2023 · How Long Will Phentermine Last. This drug’s side effects are mild, including fatigue, dizziness, headache, restlessness, nervousness, impotence, sleepiness, and nausea. Phentermine is generally prescribed by doctors and used for depression that is not responding to other treatments. The drug is also used as a weight-loss aid. Feb 3, 2023 · Phentermine alone is designed for short-term use only, as there are few long-term studies on its safety. One study observed that people experienced no significant side effects when they took ... Mar 9, 2020 · However, the EMA has not approved this medication due to its abuse potential, the lack of long-term data on the cardiovascular effects of phentermine, and the cognitive side effects of topiramate—attention, language, and memory impairment . As this drug combination contains phentermine, it is a controlled DEA schedule IV substance. Jan 12, 2023 · Qsymia works by reducing your appetite. In initial studies, Qsymia helped about 70% of adults lose at least 5% of their body weight after 1 year. Close to 50% of participants lost at least 10% of their body weight. When compared to Contrave, researchers found that Qsymia is usually the more effective option. 3. On July 17, 2012, the FDA approved a tablet combining phentermine plus extended-release topiramate (Qsymia, Vivus) for weight loss. Phentermine has been used for weight loss, and topiramate is an antiepileptic agent that has been commonly associated with weight loss as a side effect. The doses approved for weight reduction are lower than either ... Phentermine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phentermine belongs to the group of medicines known as appetite suppressants. This medicine is available only with your doctor's prescription.Aug 22, 2021 · Indeed, in the wake of the fen-phen problems, the FDA rejected all drug company efforts to win approval for new weight-loss drugs between 1999 and 2012. Since then, it has approved four drugs for ... Feb 14, 2023 · Summary. Commonly reported side effects of orlistat include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. At 6 months, a year, and 2 years after starting phentermine, weight loss was clinically significantly greater among people who used the medication longer-term (more than a year) or medium-term (more than112 days but less than a year) than in people who used it for only 3 months.Jan 16, 2023 · Qsymia is significantly more expensive than phentermine-only pills, costing about $200 per month without insurance. The combined pill has a long list of potential side effects, including severe birth defects if taken while pregnant. This is a newer medication (FDA approval in 2012), so long-term side effects remain relatively unknown. Feb 28, 2023 · The Saxenda Savings Card allows you to pay as little as a $25 copay or save up to $200 per Saxenda prescription. The Savings Card program allows for up to 12 benefits annually. There are eligibility requirements, and other restrictions apply. According to GoodRX, out-of-pocket prices range from $1332.59 to $1432.91. Jan 25, 2021 · These are the most common Topamax side effects, according to the manufacturer: Loss of appetite, changes in taste, weight loss, stomach pain, and even anorexia. GI side effects (nausea, diarrhea, indigestion) Tiredness. Paresthesia (tingling or prickling sensations) Speech problems. Cognitive dysfunction (trouble with memory and thinking) Upper ... The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy)—for long-term use. May 8, 2023 · In clinical studies, patients lost the most weight after taking Contrave for 36 weeks and maintained weight loss through 56 weeks. In terms of phentermine weight loss, studies were only done for a short period of time. Once you stop phentermine, your appetite will return to normal. As a result, weight gain may occur. It does not making you lose than reaching the idea, it is a compound that can be able to lose weight. It also leads to by increasing their absorption of physical activity and improvement Qsymia Long Term Side EffectsQsymia (phentermine and topiramate) is a weight loss medication used to help people who are overweight or obese, along with diet and exercise, to lose weight and keep the weight off. Common side effects of Qsymia include sensations of pricking, burning, tingling, or numbness of the skin; dizziness, blurred vision, fatigue, indigestion, urinary tract infections (UTIs), headache, nausea, back ... Jan 11, 2023 · In general, Phentermine chemicals do have side effects on long-term treatment. One of the most common side effects is dry mouth. Aside from this, you may also experience nervousness or jitteriness ... Other side effects. Some side effects of phentermine / topiramate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ...Topamax dosage for migraines. For people ages 12 and older, the recommended total daily dose for preventing migraines is 100 mg per day, divided into two doses. 6. Topamax can be prescribed for weight loss. Generic Topamax (topiramate) is used in combination with phentermine in a weight loss medication called Qsymia.Apr 8, 2013 · PHEN is a noradrenergic drug, which is theorized to affect food intake primarily via the enhancement of norepinephrine release and possibly via the blockade of norepinephrine reuptake as well. It has been available in the US since 1959 for short-term (generally regarded as 12 weeks) treatment of obesity in dose range of 15 mg/day to 37.5 mg/day. Nov 15, 2022 · diarrhea. dry mouth and tongue. bad taste in your mouth. constipation*. headaches*. mild allergic reaction *†. * To learn more about this side effect, see the “Side effects explained ... In clinical studies, phentermine-topiramate reduced body weight by 8.6% to 9.4% more than placebo using a conservative ITT analysis.108. Phentermine-topiramate carries risks of several serious side effects. Notably, topiramate is a recognized teratogen, at least at the higher doses used for the treatment of epilepsy.Apr 21, 2022 · Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain. diarrhea. dry mouth and tongue. bad taste in your mouth. constipation*. headaches*. mild allergic reaction *†. * To learn more about this side effect, see the “Side effects explained ...Jan 11, 2023 · In general, Phentermine chemicals do have side effects on long-term treatment. One of the most common side effects is dry mouth. Aside from this, you may also experience nervousness or jitteriness ... Common side effects of phentermine and topiramate may include: joint pain, ankle sprain; flu -like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems ( insomnia ); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, thoughts about ...After stopping phentermine, some people experience feelings of weariness and fatigue due to the sudden lack of chemical stimulation. If you are tired after stopping phentermine, take care to: Get enough sleep. Fuel your body with healthy foods: avoid high-fat, high-carb, and high-sugar goods that may worsen fatigue. Stay lightly active.Mar 13, 2023 · weight loss. impaired taste (changes in how things taste) trouble with memory. More common side effects in people taking Topamax for epilepsy include: tingling in the legs and arms. loss of ... As long as you are not taking the medication continuously with no breaks, and will stop the medication eventually, I believe that this is a safe treatment for you. That being said, you mentioned 5 years in the beginning of the question. If you have been taking the medication 3 months on, 1 month off for 5 years, I would consider that long term ...Qsymia's results have been clinically tested in two long-term studies with ... QSYMIA CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING: Birth defects (cleft lip/cleft palate). If you take Qsymia during ... This combination consists of fixed lower doses of phentermine and topiramate (3.75/23, 7/46, 11.25/69 and 15/92 mg) and is available in capsules under the brand name Qsymia. Common side effects of phentermine include nervousness, excitability, insomnia, headache, dry mouth, sweating, tachycardia, palpitations, nausea, constipation, and thirst.What Is Wegovy? Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e ...4. Avoid alcohol. Avoid drinking alcohol while taking Qsymia as it can increase your risk of serious side effects, such as central nervous system depression, and an increase in your risk of falls. 5. Don’t skip meals. Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia). 6. Objective: The aim of this work was to study weight loss and risk of cardiovascular disease (CVD) or death associated with longer-term phentermine use. Methods: Using electronic health record data, 13,972 adults were identified with a first phentermine fill in 2010 to 2015, creating exposure categories according to a patient's duration of use (referent: ≤ 3 months).Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use.The Bottom Line. Qsymia is a prescription-only weight loss medication that, when used in conjunction with diet and exercise, has a proven track record in overweight and obese individuals. The most common adverse effects are abnormal skin sensations, dizziness, altered taste, insomnia, constipation, and dry mouth, more severe issues can occur.

Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ... . Cos 90

Oct 26, 2022 · Common Qsymia side effects may include: joint pain, ankle sprain; flu-like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems (insomnia); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, ... As long as you are not taking the medication continuously with no breaks, and will stop the medication eventually, I believe that this is a safe treatment for you. That being said, you mentioned 5 years in the beginning of the question. If you have been taking the medication 3 months on, 1 month off for 5 years, I would consider that long term ...The FDA lists its typical side effects as possibly including nausea, dry mouth, diarrhea, GERD, and dry eye. 1 REPLY Updated December 26, 2021. Qsymia side effects after break. I was on Qsymia for about 16 months with no side effects. I lost 40 pounds at that time.Common side effects of Qsymia include: constipation, insomnia, nasopharyngitis, paresthesia, mood disorder, sleep disorder, and xerostomia. Other side effects include: urinary tract infection, anxiety, blurred vision, depression, dizziness, fatigue, influenza, nausea, increased serum creatinine, and dysgeusia.In clinical studies, phentermine-topiramate reduced body weight by 8.6% to 9.4% more than placebo using a conservative ITT analysis.108. Phentermine-topiramate carries risks of several serious side effects. Notably, topiramate is a recognized teratogen, at least at the higher doses used for the treatment of epilepsy.How Long Will Phentermine Last. This drug’s side effects are mild, including fatigue, dizziness, headache, restlessness, nervousness, impotence, sleepiness, and nausea. Phentermine is generally prescribed by doctors and used for depression that is not responding to other treatments. The drug is also used as a weight-loss aid.Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain.Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances.May 15, 2023 · On the positive side, lower doses of semaglutide, the active ingredient in Wegovy, have been used to treat diabetes for several years now, though UpToDate, a site that aggregates research about treatments to support decision-making by physicians, notes that there have been very few trials lasting more than four years, so the long-term safety of ... .

Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ... . Cos 90

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